RT Journal
A1 Rebolledo, Brian J.
A1 Unnanuntana, Aasis
A1 Lane, Joseph M.
T1 Bilateral Pathologic Hip Fractures Associated with Antiretroviral TherapyA Case Report
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2011
FD July 20
VO 93
IS 14
SP e78 1
OP 6
DO 10.2106/JBJS.J.00885
UL http://dx.doi.org/10.2106/JBJS.J.00885
AB 

      The use of antiretroviral medications in patients with human immunodeficiency virus (HIV) is highly effective in reducing HIV-related morbidity and mortality1,2. While HIV-positive patients continue to live longer with antiretroviral medications, adverse effects of long-term treatment include dyslipidemia, diabetes mellitus, and abnormalities of bone metabolism3,4. Metabolic bone disorders are common in patients with HIV infection, and many patients have premature osteoporosis and an increased risk of fracture5,6. While the mechanism of skeletal fragility in these patients remains inconclusive, antiretroviral medications have been described as a factor contributing to bone loss3,7.