RT Journal
A1 Zhang, Qing
A1 Zhao, Haitao
A1 Maheshwari, Aditya V.
A1 Cai, Lei
A1 Yu, Feng
A1 Niu, Xiaohui
T1 Isolated Cardiac Metastasis from a Histologically “Benign” Giant-Cell Tumor of the Distal End of the FemurA Case Report
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2010
FD November 17
VO 92
IS 16
SP 2725
OP 2731
DO 10.2106/JBJS.J.00042
UL http://dx.doi.org/10.2106/JBJS.J.00042
AB 
Although classified as a benign lesion, giant cell tumor of bone is known for its local aggressiveness, propensity for local recurrence, and metastasis even without sarcomatous transformation1-13. The frequency of metastases from benign giant-cell tumor of bone has been reported to range from 2% to 9% in larger series2-10. Most metastases are to the lungs, but metastases to the endobronchium, lymph nodes (regional as well as mediastinum and paraaortic), bone, skin, scalp, calf muscles, brain, liver, adrenals, kidneys, and breast have been reported1-25. We present the case of a patient with a benign giant-cell tumor of the distal end of the femur who subsequently developed an isolated cardiac metastasis. To the best of our knowledge, a cardiac metastasis from a benign giant-cell tumor has never been reported. The family members of our patient were informed that data concerning the case would be submitted for publication, and they consented.