RT Journal
A1 Padhy, Debabrata
A1 Madhuri, Vrisha
A1 Pulimood, Susanne A.
A1 Danda, Sumita
A1 Walter, Noel M.
A1 Wang, Lisa L.
T1 Metatarsal Osteosarcoma in Rothmund-Thomson SyndromeA Case Report
JF The Journal of Bone & Joint Surgery
JO The Journal of Bone & Joint Surgery
YR 2010
FD March 1
VO 92
IS 3
SP 726
OP 730
DO 10.2106/JBJS.I.00478
UL http://dx.doi.org/10.2106/JBJS.I.00478
AB 
Osteosarcoma is known to occur in association with a number of dysmorphic genetic syndromes1. Rothmund-Thomson syndrome is one such disorder, characterized by poikiloderma, small stature, sparse hair, skeletal defects, and an association with malignant lesions, particularly osteosarcoma. Thirty-six cases of osteosarcoma in patients with Rothmund-Thomson syndrome have been described in the English-language literature, to our knowledge; none of the tumors in those patients originated in the metatarsals or metacarpals2-6. We describe a case of osteosarcoma of the metatarsal in an adolescent male patient with Rothmund-Thomson syndrome. The patient and his father were informed that information concerning this case would be submitted for publication, and the father consented.