RT Journal A1 Moucha, Calin S. A1 Clyburn, Terry A1 Evans, Richard P. A1 Prokuski, Laura T1 Modifiable Risk Factors for Surgical Site Infection JF The Journal of Bone & Joint Surgery JO The Journal of Bone & Joint Surgery YR 2011 FD February 16 VO 93 IS 4 SP 398 OP 404 DO UL http://dx.doi.org/ AB Multiple risk factors for orthopaedic surgical site infection, including a wide variety of demographic, comorbid, operative, and postoperative variables, have been identified1. The patient as a host is an important risk factor for infection, and many, if not most, patients are in suboptimal health. Optimizing the patient's medical condition before surgery and eliminating or even diminishing modifiable risk factors for infection (Fig. 1) should lower the risk of surgical site infection. Direct scientific evidence showing that modification of these risk factors will lead to a decrease in surgical site infection is not readily available, and much work in this field remains to be done. It is imperative that surgeons have an extensive knowledge of modifiable risk factors affecting the wound-healing process and subsequent wound complications.