TY - JOUR T1 - Femoral Involvement by Langerhans Cell Histiocytosis Following Total Hip ArthroplastyA Case Report AU - Pui, Christine M. AU - Jergesen, Harry E. Y1 - 2011/09/07 N1 - 10.2106/JBJS.K.00020 JO - The Journal of Bone & Joint Surgery SP - e98 1 EP - 6 VL - 93 IS - 17 N2 - Langerhans cell histiocytosis (LCH), formerly called "eosinophilic granuloma," is a benign bone neoplasm that is rare in adults. It is a cellular lesion with histiocytes, plasma cells, small lymphocytes, neutrophils, giant cells, foam cells, and eosinophilic leukocytes1. The disease typically presents during childhood, with >90% of cases occurring between the ages of five and fifteen years. LCH typically presents as a lytic medullary lesion with sharply defined margins, most commonly in the skull and in the diaphyses of long bones. The pelvis is affected in 5% to 17% of reported cases2,3. SN - 0021-9355 M3 - doi: 10.2106/JBJS.K.00020 UR - http://dx.doi.org/10.2106/JBJS.K.00020 ER -