TY  - JOUR
T1  - Overcoming the Funding Challenge: The Cost of Randomized Controlled Trials in the Next Decade
AU  - Shore, Benjamin J.
AU  - Nasreddine, Adam Y.
AU  - Kocher, Mininder S.
Y1  - 2012/07/18
N1  - 10.2106/JBJS.L.00193
JO  - The Journal of Bone & Joint Surgery
SP  - 101
EP  - 106
VL  - 94
IS  - Suppl 1(E)
N2  - Abstract: 
  Randomized controlled trials (RCTs) represent the gold standard of evidence-based medicine. However, over the last several decades, the cost associated with conducting RCTs has increased dramatically. Several factors contribute to higher costs associated with clinical trials. This paper describes important barriers to conducting surgical RCTs, identifies funding sources available to finance RCTs, and suggests strategies to maintain cost-efficient study practices as we move into the next decade.
SN  - 0021-9355
M3  - doi: 10.2106/JBJS.L.00193
UR  - http://dx.doi.org/10.2106/JBJS.L.00193
ER  -