TY - JOUR T1 - Pilot Randomized Trials: Is There a Need? AU - Jeray, Kyle J. AU - Tanner, Stephanie L. Y1 - 2012/07/18 N1 - 10.2106/JBJS.L.00180 JO - The Journal of Bone & Joint Surgery SP - 15 EP - 18 VL - 94 IS - Suppl 1(E) N2 - Abstract:  A pilot randomized study is often essential to ensure the feasibility of conducting a large, randomized study. Pilot studies help to define the sample size, establish measurable outcomes, promote methodological rigor, establish the ability to recruit participants, assess the risk-benefit ratio of the treatments, and evaluate the economic viability of a definitive study. SN - 0021-9355 M3 - doi: 10.2106/JBJS.L.00180 UR - http://dx.doi.org/10.2106/JBJS.L.00180 ER -