TY - JOUR T1 - Meta-Analyses in Joint Arthroplasty: A Review of Quantity, Quality, and Impact AU - Sharma, Rajrishi AU - Vannabouathong, Christopher AU - Bains, Simrit AU - Marshall, Amanda AU - MacDonald, Steven J. AU - Parvizi, Javad AU - Bhandari, Mohit Y1 - 2011/12/21 N1 - 10.2106/JBJS.J.01289 JO - The Journal of Bone & Joint Surgery SP - 2304 EP - 2309 VL - 93 IS - 24 N2 - A meta-analysis is a comprehensive systematic review in which statistical analyses are used to combine the results of two or more homogeneous clinical trials1-4. In the paradigm of evidence-based orthopaedics, meta-analysis can be an invaluable tool to increase study power and improve precision when study results are combined appropriately5. Evidence from a meta-analysis, however, is highly dependent on the quality of the primary studies included and on the overall methodological rigor6. Meta-analyses have impacted clinical practice, paved the way for clinical practice guidelines and health policies, and guided subsequent research6,7. SN - 0021-9355 M3 - doi: 10.2106/JBJS.J.01289 UR - http://dx.doi.org/10.2106/JBJS.J.01289 ER -