TY  - JOUR
T1  - Familial predisposition for herniation of a lumbar disc in patients
who are less than twenty-one years old
Y1  - 1991/01/01
N1  - 
JO  - The Journal of Bone & Joint Surgery
SP  - 124
EP  - 128
VL  - 73
IS  - 1
N2  - The parents of sixty-three patients who were less than twenty-one years
old and who had operatively confirmed herniation of a lumbar disc were
interviewed regarding a history of sever back pain, sciatica, and herniated
disc, to determine whether aggregation of herniation of a lumbar disc
occurs in families of patients in this young age-group. The parents of
sixty-three additional patients who had a non-spinal orthopaedic diagnosis
(control group) were matched for age and sex with the study group and were
given the same interview. Of the patients who had herniation of a lumbar
disc and were less than twenty-one years old, 32 per cent had a positive
family history for that lesion compared with 7 per cent of the control
group. The relative risk of development of herniation of a lumbar disc
before the age of twenty-one years is estimated to be approximately five
times greater in patients who have a positive family history. The results
indicate a familial basis for herniation of a lumbar disc in patients who
are less than twenty-one years old.
SN  - 0021-9355
M3  - doi: 
UR  - http://dx.doi.org/
ER  -