TY - JOUR T1 - Large Clinical Trials in Musculoskeletal Trauma: Are They Possible?Lessons Learned from the International Study of the Use of Rhbmp-2 in Open Tibial Fractures AU - Csimma, Cristina AU - Swiontkowski, Marc F. Y1 - 2005/01/01 N1 - 10.2106/JBJS.D.01938 JO - The Journal of Bone & Joint Surgery SP - 218 EP - 222 VL - 87 IS - 1 N2 - SN - 0021-9355 M3 - doi: 10.2106/JBJS.D.01938 UR - http://dx.doi.org/10.2106/JBJS.D.01938 ER -