TY - JOUR T1 - Reconstruction of Large Skeletal Defects Due to Osteomyelitis with the Vascularized Fibular Graft in Children AU - Zalavras, Charalampos G. AU - Femino, Dominic AU - Triche, Rachel AU - Zionts, Lewis AU - Stevanovic, Milan Y1 - 2007/10/01 N1 - 10.2106/JBJS.E.01319 JO - The Journal of Bone & Joint Surgery SP - 2233 EP - 2240 VL - 89 IS - 10 N2 - Background: Reconstruction of large skeletal defects secondary to osteomyelitis is a challenging problem. The purpose of this study was to evaluate the outcome of the use of a vascularized fibular graft to treat such defects in children.Methods: Eight patients with a mean age of seven years and a skeletal defect with a mean length of 11.8 cm (range, 6 to 17 cm) were treated with a vascularized fibular graft. A staged protocol was used for the five patients with an active infection at the time of presentation. The first procedure consisted of radical débridement, and at the second stage a free (seven patients) or pedicled (one patient) vascularized fibular graft was used. The mean follow-up time was 5.7 years.Results: Union of the graft occurred primarily in seven of the eight patients, at a mean of 3.5 months, and after iliac crest bone-grafting in the remaining patient. There was no recurrence of deep infection. Complications developed in two patients. The mean time to full weight-bearing by the seven patients with a lower-extremity reconstruction was 8.4 months, and all patients were pain-free and able to walk without supportive devices.Conclusions: A vascularized fibular graft is a viable option for the management of large skeletal defects resulting from osteomyelitis in children.Level of Evidence: Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence. SN - 0021-9355 M3 - doi: 10.2106/JBJS.E.01319 UR - http://dx.doi.org/10.2106/JBJS.E.01319 ER -