TY - JOUR T1 - Can Vitamin C Prevent Complex Regional Pain Syndrome in Patients with Wrist Fractures? AU - Rogers, Benedict A. AU - Ricketts, David M. Y1 - 2008/02/01 N1 - JO - The Journal of Bone & Joint Surgery SP - 447 EP - 448 VL - 90 IS - 2 N2 - The paper cites an article by Kearns et al.1 to provide the steady-state level of ascorbic acid (vitamin C) with doses of 200 mg per day. However, Kearns et al. used Sprague-Dawley rats in their study. The muscles were analyzed after three hours of ischemia and one hour of reperfusion. We are not convinced that these data can be used to accurately determine the steady-state level of vitamin C in humans. SN - 0021-9355 M3 - doi: UR - http://dx.doi.org/ ER -