TY  - JOUR
T1  - Failure of Metal-on-Metal Total Hip Arthroplasty Mimicking Hip InfectionA Report of Two Cases
AU  - Mikhael, Mark M.
AU  - Hanssen, Arlen D.
AU  - Sierra, Rafael J.
Y1  - 2009/02/01
N1  - 10.2106/JBJS.H.00603
JO  - The Journal of Bone & Joint Surgery
SP  - 443
EP  - 446
VL  - 91
IS  - 2
N2  - 
New-generation metal-on-metal bearings made from cobalt-chromium alloys for use in total hip arthroplasty are now being utilized worldwide. A hypersensitivity reaction to a metal-on-metal bearing is a rare but reported complication and is thought to be a novel mode of failure of these implants1,2. These reactions were initially observed in patients with first-generation bearings and are now being reported in association with the second-generation metal-on-metal bearings currently in use3-5. Characteristic histological changes in the periprosthetic tissues obtained during revision surgical procedures in these patients have suggested the development of an immunological response2,6.

SN  - 0021-9355
M3  - doi: 10.2106/JBJS.H.00603
UR  - http://dx.doi.org/10.2106/JBJS.H.00603
ER  -