TY - JOUR T1 - Perils of Intravascular Methylprednisolone Injection into the Vertebral Artery AU - Wainger, Brian J. AU - Rathmell, James P. Y1 - 2009/05/01 N1 - JO - The Journal of Bone & Joint Surgery SP - 1277 EP - 1278 VL - 91 IS - 5 N2 - We commend Dr. Okubadejo and colleagues for the article "Perils of Intravascular Methylprednisolone Injection into the Vertebral Artery. An Animal Study" (2008;90:1932-8). They show a convincing association between intra-arterial injection of particulate steroid and catastrophic neurological injury. This study should help to eliminate remaining questions about the mechanism of injury. We offer a caution about judging the permanency of neural injury and issue a call for further study of the safety and effectiveness of nonparticulate steroids, particularly dexamethasone. SN - 0021-9355 M3 - doi: UR - http://dx.doi.org/ ER -