TY - JOUR T1 - Design, Conduct, and Interpretation of Nonrandomized Orthopaedic Studies: A Practical Approach(All) Evidence Matters AU - Bhandari, Mohit AU - Morshed, Saam AU - TornettaIII, Paul AU - Schemitsch, Emil H. Y1 - 2009/05/01 N1 - 10.2106/JBJS.H.01747 JO - The Journal of Bone & Joint Surgery SP - 1 EP - 1 VL - 91 IS - Supplement_3 N2 - The most sophisticated practice of evidence-based orthopaedics requires a clear delineation of relevant clinical questions, a thorough search of the literature relating to the questions, a critical appraisal of available evidence and its applicability to the clinical situation, and a balanced application of the conclusions to the clinical problem. The balanced application of the evidence (i.e., clinical decision-making) is the central point of practicing evidence-based medicine and involves an integration of our clinical expertise and judgment with patients' and societal values and with the best available research evidence. SN - 0021-9355 M3 - doi: 10.2106/JBJS.H.01747 UR - http://dx.doi.org/10.2106/JBJS.H.01747 ER -