TY - JOUR T1 - Prenatal Diagnosis and Treatment of Congenital Differences of the Hand and Upper Limb AU - Bae, Donald S. AU - Barnewolt, Carol E. AU - Jennings, Russell W. Y1 - 2009/07/01 N1 - 10.2106/JBJS.I.00072 JO - The Journal of Bone & Joint Surgery SP - 31 EP - 39 VL - 91 IS - Supplement_4 N2 - Prenatal detection of congenital abnormalities is increasing, along with the evolving technology and widespread use of ultrasonography in prenatal screening. Musculoskeletal anomalies are noted during prenatal ultrasonography in approximately six of every 1000 pregnancies (0.6%), although approximately 1% to 2% of all newborns have some type of congenital difference and the musculoskeletal system is affected in 10% to 20% of these infants (0.1% to 0.4% of newborns)1,2. The prevalence of skeletal dysplasia is 2.4 per 10,000 live births (0.02%), and the prevalence of limb deficiency is 0.49 per 10,000 births (<0.01%)1,3-5. SN - 0021-9355 M3 - doi: 10.2106/JBJS.I.00072 UR - http://dx.doi.org/10.2106/JBJS.I.00072 ER -