TY  - JOUR
T1  - Osteochondral Lesions of the Knee: A New One-Step Repair Technique with Bone-Marrow-Derived Cells
AU  - Buda, Roberto
AU  - Vannini, Francesca
AU  - Cavallo, Marco
AU  - Grigolo, Brunella
AU  - Cenacchi, Annarita
AU  - Giannini, Sandro
Y1  - 2010/12/01
N1  - 10.2106/JBJS.J.00813
JO  - The Journal of Bone & Joint Surgery
SP  - 2
EP  - 11
VL  - 92
IS  - Supplement_2
N2  - 
Osteochondral lesions of the knee are defects of the cartilaginous surface and underlying subchondral bone, most frequently traumatic in origin1. These lesions are predominantly located on the medial femoral condyle, and associated ligamentous or meniscal pathology is reported in 40% of cases2,3 (Fig. 1). Biomechanical studies have demonstrated increased stress concentration on the rim of the osteochondral defect, which may have important implications for cartilage longevity4. Due to poor hyaline cartilage repair capability, larger osteochondral lesions of the knee are associated both with immediate significant clinical impairment and with symptoms appearing approximately one decade earlier than the degenerative cartilage changes that are associated with idiopathic osteoarthritis5.

SN  - 0021-9355
M3  - doi: 10.2106/JBJS.J.00813
UR  - http://dx.doi.org/10.2106/JBJS.J.00813
ER  -