TY  - JOUR
T1  - Isolated Cardiac Metastasis from a Histologically “Benign” Giant-Cell Tumor of the Distal End of the FemurA Case Report
AU  - Zhang, Qing
AU  - Zhao, Haitao
AU  - Maheshwari, Aditya V.
AU  - Cai, Lei
AU  - Yu, Feng
AU  - Niu, Xiaohui
Y1  - 2010/11/17
N1  - 10.2106/JBJS.J.00042
JO  - The Journal of Bone & Joint Surgery
SP  - 2725
EP  - 2731
VL  - 92
IS  - 16
N2  - 
Although classified as a benign lesion, giant cell tumor of bone is known for its local aggressiveness, propensity for local recurrence, and metastasis even without sarcomatous transformation1-13. The frequency of metastases from benign giant-cell tumor of bone has been reported to range from 2% to 9% in larger series2-10. Most metastases are to the lungs, but metastases to the endobronchium, lymph nodes (regional as well as mediastinum and paraaortic), bone, skin, scalp, calf muscles, brain, liver, adrenals, kidneys, and breast have been reported1-25. We present the case of a patient with a benign giant-cell tumor of the distal end of the femur who subsequently developed an isolated cardiac metastasis. To the best of our knowledge, a cardiac metastasis from a benign giant-cell tumor has never been reported. The family members of our patient were informed that data concerning the case would be submitted for publication, and they consented.

SN  - 0021-9355
M3  - doi: 10.2106/JBJS.J.00042
UR  - http://dx.doi.org/10.2106/JBJS.J.00042
ER  -